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Cytokines and Growth Factors Cytokines and Growth Factors

Cat.No.  Name Information
M9370 Recombinant Human TNF α (HEK293, C-His) Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections.
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml
M9391 Recombinant Human TGF-β1 (CHO) Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.
M9241 Recombinant Human EPO Protein (CHO) Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells.
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) Recombinant Human PDGF-BB Protein (HEK293)
M9987 Recombinant Human PDGF-AA Protein (HEK293) Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.
M9981 Recombinant Human IL-11 Protein (E. coli) Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.
M21094 Recombinant Rat IL-1β (E. coli) Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg.
M10022 Recombinant Mouse GM-CSF Protein (CHO) Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg.
M54739 Recombinant Human ICA 512/PTPRN Protein (80AA&94AA, E.coli, N-6His) ICA 512/PTPRN Protein belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. ICA 512/PTPRN implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions.
M54738 Recombinant Human ICA 512/PTPRN Protein (293AA, E.coli, N-6His) ICA 512/PTPRN Protein belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. ICA 512/PTPRN implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions.
M54737 Recombinant Human GAD67 Protein (Baculovirus-Insect, C-His) GAD67 (GAD1) is a member of thegroup II decarboxylase family. GAD67 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker.
M54732 Recombinant Human GAS6 Protein (HEK293, C-6His) GAS6 (Growth arrest-specific protein 6) also known as AXL receptor tyrosine kinase ligand, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest.
M54731 Recombinant Mouse GAS6 Protein (HEK293, C-His) GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells.
M54699 Recombinant Human Lactoferrin/LTF Protein (HEK293, C-6His) Lactoferrin (LTF) is a major iron-binding protein in exocrine fluid and controls the level of free iron in the blood and external secretions. It exhibits multiple antibacterial effects by chelating iron and disrupting bacterial membranes.
M54637 Recombinant Mouse Thioredoxin/SASP Protein (E. coli) Thioredoxin/SASP Protein participates in a variety of redox reactions and can use its active dithiol center for reversible oxidation and disulfide bond formation. It catalyzes important dithiol-disulfide exchanges and plays a key role in the S-nitrosylation of cysteine residues in response to intracellular nitric oxide.
M54636 Recombinant Human Thioredoxin/SASP Protein (E.coli, N-6His) Recombinant Human Thioredoxin/SASP Protein participates in a variety of redox reactions and can use its active dithiol center for reversible oxidation and disulfide bond formation. It catalyzes important dithiol-disulfide exchanges and plays a key role in the S-nitrosylation of cysteine residues in response to intracellular nitric oxide.
M54580 Recombinant Human CXCL4/PF-4 Protein (HEK293, C-6His) Human CXCL4/PF-4 is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4/PF-4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair.
M54564 Recombinant Mouse/Rat TGF-beta 2 Protein (HEK293) Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure.
M54561 Recombinant Mouse FABP4 Protein (HEK293, C-His) FABP4 is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family.
M54522 Recombinant Human IFN-α 2b Protein (E. coli) IFN-α 2b (Interferon-Alpha 2b) [Cys24-Glu188 (Lys46Arg)] produced by leukocytes is a member of Interferon family. IFN-alpha is mainly involved in innate immune response against a broad range of viral infections.
M49940 Recombinant Rat IL-2 (HEK293, C-6His) Interleukin-2 (IL-2) is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
M49920 Recombinant Mouse VCAM-1 Protein (HEK293, C-Fc) Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction.
M49919 Recombinant Human VCAM-1 Protein (HEK293, C-6His) VCAM-1 is a single-pass type I membrane protein, and mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate.
M49918 Recombinant Mouse GSK-3 beta Protein (Baculovirus-Insect, His Tag) GSK-3 beta/GSK3B Protein is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. GSK3B participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB, and the transcription factor JUN.
M49916 Recombinant Human GSK-3 beta Protein (Baculovirus-Insect, His Tag) GSK-3 beta/GSK3B Protein is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. GSK3B participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB, and the transcription factor JUN.
M49479 Recombinant Human IFN-γ Protein (E. coli) IFN-γ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. Human Interferon gamma (hIFN-γ) is amacrophage‐activating factor. IFN-γ is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.
M49418 Recombinant Human VEGF 121 Protein (E.coli) Human VEGF121 belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF121 is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessels and endothelial cell growth, increasing microvascular permeability, promoting cell migration and inhibiting apoptosis.
M49417 Recombinant Mouse PLA2G2A Protein (Yeast, C-His) PLA2G2A, is a peripheral membrane protein that belongs to the phospholipase A2 family. PLA2G2A plays a role in anti-bacterial defense, inflammation and eicosanoid generation, in clearance of apoptotic cells, and in the Wnt signaling pathway.




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