| Cat.No. | Name | Information |
|---|---|---|
| M9370 | Recombinant Human TNF α (HEK293, C-His) | Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections. |
| M9413 | Recombinant Human VEGF165 Protein (HEK293, C-His) | Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability. |
| M10922 | Recombinant Mouse TGF-beta 1 Protein (Human Cells) | Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml |
| M9391 | Recombinant Human TGF-β1 (CHO) | Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. |
| M9241 | Recombinant Human EPO Protein (CHO) | Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells. |
| M9402 | Recombinant Human PDGF-BB Protein (HEK293, C-His) | Recombinant Human PDGF-BB Protein (HEK293) |
| M9987 | Recombinant Human PDGF-AA Protein (HEK293) | Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. |
| M9981 | Recombinant Human IL-11 Protein (E. coli) | Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. |
| M21094 | Recombinant Rat IL-1β (E. coli) | Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg. |
| M10022 | Recombinant Mouse GM-CSF Protein (CHO) | Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg. |
| M55375 | Recombinant Human CD143/ACE (E. coli, N-GST) | CD143/ACE Protein is a recombinant human Angiotensin I-converting enzyme (ACE, CD143) which hydrolyzes small peptides such as angiotensin I, bradykinin, substance P, LH-RH and several others and thus plays a key role in blood pressure regulation and vascular remodeling. ACE plays a crucial role in blood pressure regulation, vascular remodeling, and immunity. |
| M55374 | Recombinant Human Neprilysin (HEK293, N-8His) | Neprilysin/CD10 (MME; NEP) is a zinc metallopeptidase expressed at the cell surface of a variety of cells. Neprilysin/CD10 (MME) has been shown to be involved in the degradation of enkephalins in the mammalian brain and the inactivation of circulating atrial natriuretic peptide. |
| M55373 | Recombinant Human THOP1 (E.coli, C-6His) | Thimet Oligopeptidase (THOP1) is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments. |
| M55364 | Recombinant Mouse IL-22 (HEK293, C-mFc) | Interleukin-22 (IL-22) is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. |
| M55362 | Recombinant Human REG4 Protein (HEK293, C-6His) | Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium. |
| M55361 | Recombinant Mouse REG4 Protein (HEK293, His Tag) | Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium. |
| M55355 | Recombinant Mouse IGF-1 (E.coli, C-6His) | Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors. |
| M55353 | Recombinant Human BMP-9 Protein (E. coli, His Tag) | Bone Morphogenetic Protein-9 (BMP-9), also known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-9/GDF-2 selectively signals through ACVRL1 in endothelial cells. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1. |
| M55351 | Recombinant Human IL-4 Protein (HEK293) | Interleukin-4 (IL-4) regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. |
| M55350 | Recombinant Human IL-13 Protein (HEK293, C-Fc) | Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. |
| M55333 | Recombinant Mouse GDF15 (HEK293, N-8His-Flag) | Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenitors and introduced as a putative placental mediator of embryonic development. |
| M55327 | Recombinant Mouse CX3CL1 Protein (HEK293, C-6His) | C-X3-C motif Chemokine 1 (CX3CL1; Fractalkine) is a single-pass type I membrane protein which belongs to the intercrine delta family. The protein may play a role in regulating leukocyte adhesion and migration processes at the endothelium. |
| M55325 | Recombinant Human IL-29/IFN-λ1 (HEK293, C-10His) | Interleukin-29 (IL-29; IFN-λ1) is a cytokine with immunomodulatory activity. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. |
| M55314 | Recombinant Mouse Decorin Protein (HEK293, C-6His) | Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R. |
| M55313 | Recombinant Human Decorin Protein (HEK293) | Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R. |
| M55312 | Recombinant Human Decorin Protein (HEK293, C-6His) | Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R. |
| M55307 | Recombinant Human TIM-4 Protein (HEK293, C-6His) | T-cell Immunoglobulin and Mucin Domain-containing Protein 4(TIM-4) belongs to the immunoglobulin superfamily. TIM-4 is expressed by macrophages and mature dendritic cells but not by lymphocytes. it is Involved in regulating T-cell proliferation and lymphotoxin signaling. |
| M55299 | Recombinant Human FLT3L (HEK293, C-6His) | Fms-like Tyrosine Kinase 3 Ligand (FLT3L) is a hematopoietic four helical bundle cytokine. Flt‑3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts. |
| M55293 | Recombinant Mouse RANKL (E. coli) | RANKL is a member of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. Tnfsf11 is involved in many fundamental biological processes, such as acting as a regulator of interactions between T cells and dendritic cells, regulating T cell-dependent immune responses and enhancing bone resorption in malignant humoral hypercalcemia. It enhances the ability of dendritic cells to stimulate the proliferation of naive T cells. |
| M55236 | Recombinant Mouse LTBR Protein (HEK293, C-Fc) | Lymphotoxin Beta Receptor is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs. The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. |
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