Free shipping on all orders over $ 500

Recombinant Mouse TGF-beta 1 Protein (Human Cells)

Cat. No. M10922

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse TGF-beta 1 Protein (Human Cells) Structure
Synonym:

TGF-β1, Mouse

Size Price Availability Quantity
5ug USD 180  USD180 In stock
10ug USD 280  USD280 In stock
50ug USD 800  USD800 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/μg
  • COA
  • MSDS
Biological Activity

TGF-beta 1 protein, Mouse is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis.

ED50 is 5-25 pg/ml, measured by its ability to inhibit IL-4-dependent proliferation of TF-1 human erythroleukemic cells.


Accession # P04202

Apparent Molecular Weight: ~12.8 kDa, reducing conditions

Endotoxin < 1 EU/μg

Lyophilized from a 0.2 μm filtered solution in 4 mM HCl.

Product Citations
Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in ddH2O up to 100 μg/ml
Storage Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C.
References

[1] Yen-Ting Chen, et al. J Clin Invest. Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts

[2] Xiaomeng Wang, et al. Nature. LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling

[3] Daisuke Sugiyama, et al. Mech Dev. TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts

[4] Li Xiao, et al. Front Biosci (Landmark Ed). TGF-beta 1 induced fibroblast proliferation is mediated by the FGF-2/ERK pathway

[5] Zhan Jiang, et al. bioRxiv. Hypoxia induced oxidative stress and endoplasmic reticulum stress promoted myocardial cell fibrosis

Related Cytokines and Growth Factors Products
Recombinant Human HGF (CHO-expressed)

Recombinant human Hepatocyte Growth Factor (rhHGF) , also known as hepatopoietin-A and scatter factor, is a pleiotropic mitogen belonging to the peptidase S1 family (plasminogen subfamily). It is produced by mesenchymal cells and acts on epithelial cells, endothelial cells and haemopoietic progenitor cells.

Recombinant Human RIPK3 Protein (E. coli, N-His)

RIPK3 is a kinase that controls necroptosis and apoptosis. In necroptosis, activated by TNF-α and ZBP1, RIPK3 phosphorylates MLKL, leading to membrane damage. Necroptosis is dependent on receptor-interacting protein kinase 3 (RIPK3), a protein shown to play an important role in experimental models of critical illness. RIPK3 promotes kidney tubular injury via mitochondrial dysfunction. The FAO-dependent RIPK3 mediates pathogenesis of acute lung injury.

Recombinant Influenza B Hemagglutinin/HA Protein (HEK293, C-His)

Recombinant Influenza B Hemagglutinin / HA Protein is a homotrimer that recognizes target cells in vertebrates and does so by binding to salivary acid-containing receptors on these cells. When it binds to the target cell, it causes the host inner membrane to fuse with the viral membrane, thereby facilitating the entry of the viral genome into the target cell.

Recombinant Human FGF-9 (E. coli)

Fibroblast Growth Factor-9 (FGF-9) is a heparin binding growth factor that belongs to the fibroblast growth factor (FGF) family. ED50 < 2.0 ng/ mL, determined by 3T3 cell proliferation assay, corresponding to > 5.0× 105 units/mg.

Recombinant Human CXCL13/BCA-1 (E. coli)

CXCL13, also known as B-lymphocyte chemoattractant (BLC), is a CXC chemokine that is constitutively expressed in secondary lymphoid organs. Recombinant human CXCL13 is a single non-glycosylated polypeptide chain containing 87 amino acids and mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. Determined by a chemotaxis bioassay using human B cells, the biological activity is in a concentration range of 1.0-10 ng/ml.

  Catalog
Abmole Inhibitor Catalog




Keywords: Recombinant Mouse TGF-beta 1 Protein (Human Cells), TGF-β1, Mouse supplier, Cytokines and Growth Factors, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.