All AbMole products are for research use only, cannot be used for human consumption.
Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ is released from degranulating platelets and secreted by all of the major cell types participating in the repair process, including lymphocytes, macrophages, endothelial cells, smooth muscle cells, epithelial cells, and fibroblasts. Mammals express three isoforms of TGFβ designated TGFβI, TGFβ2, and TGFβ3; TGFβ1 is the most abundant isoform in all tissues, and in human platelets it is the only isoform of the peptide. TGFβ1 has immunomodulatory effects. TGFβ1 has profibrogenic effects.
Measured in ability to inhibit the mouse IL-4-dependent proliferation of HT-2 cells, the ED50 is < 0.2 ng/ml.
DNA sequence encoding human TGF-β1 (Ala279-Ser390) expressed.
Apparent Molecular Weight: 12~13 KDa, reducing conditions
Endotoxin: <0.1EU/μg
Cancer Res. 2025 Aug 01; .
Exon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1-Mediated Phosphoenolpyruvate Production
Recombinant Human TGF-β1 (CHO) purchased from AbMole
Cell Biol Toxicol. 2025 Jul 01;41(1):110.
TEAD4-mediated upregulation of LPAR3 augments hepatic stellate cell activation in portal hypertension
Recombinant Human TGF-β1 (CHO) purchased from AbMole
Curr Pharm Biotechnol. 2025 Oct 01; .
Discoidin Domain Receptor 1 in Colonic Epithelial Cells: A Paracrine Driver of Colonic Fibrosis
Recombinant Human TGF-β1 (CHO) purchased from AbMole
Toxicol Appl Pharmacol. 2024 Jun 27.
Serum deprivation protein response intervenes in the proliferation, motility, and extracellular matrix production in keloid fibroblasts by blocking the amplification of TGF-β1/SMAD signal cascade via ERK1/2
Recombinant Human TGF-β1 (CHO) purchased from AbMole
Eur J Med Res. 2024 Dec 28;29(1):631.
MicroRNA-668 alleviates renal fibrosis through PPARα/PGC-1α pathway
Recombinant Human TGF-β1 (CHO) purchased from AbMole
Patent. CN117844735A 2024 Apr 09.
Patent. CN117844735A
Recombinant Human TGF-β1 (CHO) purchased from AbMole
Patent. CN118667755A 2024 Sep 20.
Patent. CN118667755A
Recombinant Human TGF-β1 (CHO) purchased from AbMole
Patent. CN114606192B 2023 Aug 08.
Patent. CN114606192B
Recombinant Human TGF-β1 (CHO) purchased from AbMole
Allergol Immunopathol (Madr). 2022 Mar 1;50(2):104-114.
6-Gingerol, a functional polyphenol of ginger, reduces pulmonary fibrosis by activating Sirtuin1
Recombinant Human TGF-β1 (CHO) purchased from AbMole
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Source | Recombinant Human TGF-β1 (AbMole) |
| Method | SDS-PAGE analyses | |
| Cell Lines | ||
| Concentrations | ||
| Incubation Time | ||
| Results | The purity is > 97 % by SDS-PAGE analyses. |
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in 4mM HCl or PBS to a concentration not less than 100 μg/mL. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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| Recombinant Human CXCL13/BCA-1 (E. coli)
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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