| Cat.No. | Name | Information |
|---|---|---|
| M9370 | Recombinant Human TNF α (HEK293, C-His) | Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections. |
| M9413 | Recombinant Human VEGF165 Protein (HEK293, C-His) | Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability. |
| M10922 | Recombinant Mouse TGF-beta 1 Protein (Human Cells) | Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml |
| M9391 | Recombinant Human TGF-β1 (CHO) | Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. |
| M9241 | Recombinant Human EPO Protein (CHO) | Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells. |
| M9402 | Recombinant Human PDGF-BB Protein (HEK293, C-His) | Recombinant Human PDGF-BB Protein (HEK293) |
| M9987 | Recombinant Human PDGF-AA Protein (HEK293) | Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. |
| M9981 | Recombinant Human IL-11 Protein (E. coli) | Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. |
| M21094 | Recombinant Rat IL-1β (E. coli) | Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg. |
| M10022 | Recombinant Mouse GM-CSF Protein (CHO) | Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg. |
| M55680 | Recombinant Human PSA/KLK3 Protein (HEK293, 244AA, C-6His) | Recombinant Human PSA/KLK3 is a member of serine proteases having diverse physiological functions. Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. |
| M55679 | Recombinant Human CA125 Protein (HEK293, C-6His) | CA125 is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. CA125 binds galectin-1 on immune cells and enhances its expression on tumor cells. CA125-expressing tumors adhere to NK cells, down-regulate CD16 and suppress NK response, which may promote immune evasion. |
| M55674 | Recombinant Mouse Neuroserpin Protein (HEK293, C-His) | Neuroserpin, also known as SERPINI1, is a secreted protein that belongs to the serpin family. Neuroserpin is a serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. Neuroserpin may be involved in the formation or reorganization of synaptic connections, as well as synaptic plasticity in the adult nervous system. |
| M55668 | Recombinant Human PTGDS Protein (HEK293, C-6His) | Prostaglandin-D2 Synthase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. |
| M55661 | Recombinant Human IFNAR1 (HEK293, C-6His) | Interferon Alpha/Beta Receptor 1 (IFNAR1) interacts very weakly or not at all with type 1 interferons and does not stably interact with IFN-α/β R2. Ligands associate with IFN-α/β R2, and this complex subsequently forms a stable ternary assembly with IFN-α/β R1. IFN-α/β R1 also associates with IFN-γ R2 even in the absence of IFN-γ stimulation. |
| M55646 | Recombinant Human CDH16 Protein (HEK293, C-6His) | Cadherin-16 (CDH16) is a single-pass type I membrane protein which contains six cadherin domains. CDH16 is exclusively expressed in kidney, where the protein functions as the principal mediator of homotypic cellular recognition. It plays a role in the morphogenic direction of tissue development. |
| M55644 | Recombinant Human CDH17 Protein (HEK293, C-6His) | Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherin-17 plays a role in the morphological organization of liver and intestine and involved in intestinal peptide transport. |
| M55632 | Recombinant Human IL-7 Protein (HEK293, C-6His) | Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction. |
| M55631 | Recombinant Human IL-7 Protein (E. coli) | Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction. |
| M55630 | Recombinant Human Desmoplakin/DSP Protein (E. coli, N-His) | DSP proteins are major components of desmosomes and are critical for the structural integrity of various tissues. In cardiomyocytes, DSP regulates profibrotic gene expression through MAPK14/p38 MAPK activation and increased TGFB1 protein. |
| M55622 | Recombinant Human BMPRIA/ALK-3/CD292 Protein (HEK293, C-His) | BMPR1A/ALK-3/CD292 protein is expressed in the epithelium during branching morphogenesis. It is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta (TGF-β) superfamily. BMPR1A/ALK-3 plays an essential role in the formation of embryonic ventral abdominal wall, and abrogation of BMP signaling activity due to gene mutations in its signaling components could be one of the underlying causes of omphalocele at birth. The type IA BMP receptor, ALK-3 was specifically required at mid-gestation for normal development of the trabeculae, compact myocardium, interventricular septum, and endocardial cushion. |
| M55621 | Recombinant Human ACVR2A Protein (HEK293, C-6His) | Activin Receptor Type-2A (ACVR2A) is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. |
| M55567 | Recombinant Human ROR2 (HEK293, C-6His) | Receptor Tyrosine Kinaselike Orphan Receptor 2(ROR2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. ROR2 promotes osteogenesis, binds YWHAB and Interacts with WTIP. |
| M55559 | Recombinant Human IL-11 Protein (E. coli, N-His) | Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. |
| M55556 | Recombinant Human IL-11 Protein (Yeast) | Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. |
| M55404 | Recombinant Mouse Pleiotrophin/PTN (HEK293, C-6His) | Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated with neuronal development or stresses such as brain ischemia and Parkinson’s disease. |
| M55400 | Recombinant Rat FGF-basic (E. coli, Pro10-Ser154) | Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. |
| M55399 | Recombinant Rat FGF-basic (E. coli, Ala11-Ser154) | Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. |
| M55382 | Recombinant Human IL-25/IL-17E (E. coli, C-His) | Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. |
| M55381 | Recombinant Human IL-25/IL-17E (HEK293, C-6His) | Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. |
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