All AbMole products are for research use only, cannot be used for human consumption.
Withaferin A is A steroid isolated from South African drunken eggplant, which can inhibit the activity of NF-KB and target vimentin. It has anti-inflammatory and anti-tumor effects. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
J Virol. 2025 Feb 05.
The Japanese encephalitis virus NS1 protein concentrates ER membranes in a cytoskeleton-independent manner to facilitate viral replication
Withaferin A purchased from AbMole
J Virol. 2022 Jul 27;96(14):e0212721.
PRRSV infection induces gasdermin d-driven pyroptosis of porcine alveolar macrophages through NLRP3 inflammasome activation
Withaferin A purchased from AbMole
| Molecular Weight | 470.6 |
| Formula | C28H38O6 |
| CAS Number | 5119-48-2 |
| Solubility (25°C) | DMSO 4.71 mg/mL |
| Storage | 2-8°C, protect from light |
| Related NF-κB Products |
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| QNZ
QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM. |
| Caffeic Acid Phenethyl Ester
Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities. |
| Cepharanthine
Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production. |
| JSH-23
Jsh-23 is a NF-κB inhibitor, inhibited NF-κB transcriptional activity in lipopolysaccharid-stimulated macrophages RAW 264.7 with IC50 of 7.1 μM. Jsh-23 inhibited the nuclear translocation of NF-κB P65 without affecting the degradation of IκBα. |
| Methylthiouracil
Methylthiouracil is an anti-thyroid agent. Methylthiouracil inhibits TNF-α and IL-6 production and NF-κB and ERK1/2 activation. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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