All AbMole products are for research use only, cannot be used for human consumption.
Jsh-23 is a NF-κB inhibitor, inhibited NF-κB transcriptional activity in lipopolysaccharid-stimulated macrophages RAW 264.7 with IC50 of 7.1 μM. Jsh-23 inhibited the nuclear translocation of NF-κB P65 without affecting the degradation of IκBα.
Nat Commun. 2025 Jul 01;16(1):5773.
Engineering STING Nanoadjuvants for spatiotemporally-tailored innate immunity stimulation and cancer vaccination therapy
JSH-23 purchased from AbMole
Stem Cell Res Ther. 2025 Jul 18;16(1):388.
Ionizing radiation-mediated dendritic cell maturation exacerbates inflammatory response of bone marrow mesenchymal stem cells and impairs osteogenesis in radiation-induced jaw injury
JSH-23 purchased from AbMole
Adv Mater. 2023 Mar;35(10):e2209910.
Acid-Ionizable Iron Nanoadjuvant Augments STING Activation for Personalized Vaccination Immunotherapy of Cancer
JSH-23 purchased from AbMole
Journal of Biosciences and Medicines. 2022 Apr.
The Three Main SCFAs Inhibit the Inflammatory Response of A549 Cells Induced by Acinetobacter baumannii
JSH-23 purchased from AbMole
| Molecular Weight | 240.34 |
| Formula | C16H20N2 |
| CAS Number | 749886-87-1 |
| Solubility (25°C) | DMSO 28 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related NF-κB Products |
|---|
| QNZ
QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM. |
| Caffeic Acid Phenethyl Ester
Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities. |
| Cepharanthine
Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production. |
| Methylthiouracil
Methylthiouracil is an anti-thyroid agent. Methylthiouracil inhibits TNF-α and IL-6 production and NF-κB and ERK1/2 activation. |
| Bruceine A
Brucaine A (Brucea javanica A) is a natural bitter bitter compound, extracted from the dried fruit of Brucea javanica, which can act on dog scorch. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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