All AbMole products are for research use only, cannot be used for human consumption.
SHA 68 is a potent and selective non-peptide neuropeptide S receptor (NPSR) antagonist with IC50 values of 22.0 and 23.8 nM for NPSR Asn107 and NPSR Ile107, respectively. SHA 68 has limited the blood-brain barrier (BBB) penetration and the activity in neuralgia.
| Molecular Weight | 445.49 |
| Formula | C26H24FN3O3 |
| CAS Number | 847553-89-3 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Neuropeptide Receptor Products |
|---|
| JNJ-31020028
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22 rat); >100-fold selective versus human Y1/Y4/Y5 receptors. |
| BIBO 3304 trifluoroacetate
BIBO 3304 trifluoroacetate is a highly selective NPY Y 1 receptor antagonist. |
| CYM 9484
CYM 9484 is a potent NPY Y 2 receptor antagonist. |
| L-152,804
L-152,804 is a potent, selective non-peptide NPY Y 5 receptor antagonist. |
| NTNCB hydrochloride
NTNCB hydrochloride is a potent and selective non-peptidic NPY Y 5 antagonist. |
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Products are for research use only. Not for human use. We do not sell to patients.
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