All AbMole products are for research use only, cannot be used for human consumption.
Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest. Polydatin has been shown to inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. Endothelial cell studies report that Polydatin can inhibit ICAM-1 expression, elevate Ca2+, weaken white blood cell-endothelial cell adhesion, and activate KATP channels. In the present study, polydatin protects NRK-52E cells from I/R injury possibly by relieving the inflammatory response through regulation of TLR4/NF-κB signaling pathway. Polydatin regulates glucose and lipid metabolism in experimental diabetic models, the underlying mechanism is probably associated with regulating the Akt pathway. The effect of polydatin on increased Akt phosphorylation is independent of prompting insulin secretion, but dependent of increasing IRS phosphorylation.
Materials & Design. 2024 Aug 31.
Polydatin and chitosan-silver co-loaded nanocomplexes for synergistic treatment of rheumatoid arthritis via repolarizing macrophages and inducing apoptosis of fibroblast-like synoviocytes
Polydatin purchased from AbMole
Mater. Des. 2024 Aug;113287.
Polydatin and chitosan-silver co-loaded nanocomplexes for synergistic treatment of rheumatoid arthritis via repolarizing macrophages and inducing apoptosis of fibroblast-like synoviocytes
Polydatin purchased from AbMole
Patent. CN117023605B 2024 Apr 26.
Patent. CN117023605B
Polydatin purchased from AbMole
Patent. CN117023605A 2023 Nov 10.
Patent. CN117023605A
Polydatin purchased from AbMole
| Molecular Weight | 390.40 |
| Formula | C20H22O8 |
| CAS Number | 27208-80-6 |
| Solubility (25°C) | DMSO ≥ 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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