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Lys-[Des-Arg9]Bradykinin

Cat. No. M53248

All AbMole products are for research use only, cannot be used for human consumption.

Lys-[Des-Arg9]Bradykinin Structure

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Quality Control & Documentation
Biological Activity

Lys-[Des-Arg9]Bradykinin, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a Ki of 0.12 nM, 1.7 nM and 0.23 nM for human, mouse and rabbit B1 receptors, respectively.

Chemical Information
Molecular Weight 1032.2
Formula C50H73N13O11
CAS Number 71800-36-7
Solubility (25°C) Water
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related Bradykinin Receptor Products
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ELN-441958 is a potent, neutral, competitive and selective oral bioavailable bradykinin B1 receptor antagonist with a Ki of 0.26 nM against native human bradykinin B1 receptor.

SSR240612

Treatment with the kinin B1 receptor antagonist, SSR240612, provided a protective effect against organ damage by interfering with multiple target functions, including the suppression of B1R-induced inflammation and platelet aggregation.

Icatibant (HOE 140) acetate

Icatibant (HOE-140) acetate is a potent and specific peptide antagonist of bradykinin B2 receptor, with IC50 value of 1.07 nM and Ki value of 0.798 nM, respectively.

Bradykinin

Bradykinin (bradykinin) is a vasodilator active peptide produced by the kinin-releasing enzyme-kinin system that modulates inflammation by causing vasodilation, increasing vascular permeability, and stimulating prostaglandin synthesis.

Icatibant

Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.

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Keywords: Lys-[Des-Arg9]Bradykinin supplier, Bradykinin Receptor, inhibitors, activators

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