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Compound 48/80 trihydrochloride is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets.
| Molecular Weight | 629.10 |
| Formula | C32H48Cl3N3O3 |
| CAS Number | 848035-21-2 |
| Solubility (25°C) | Water 25 mg/mL (Need ultrasonic) |
| Storage | 4°C, dry, sealed |
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