All AbMole products are for research use only, cannot be used for human consumption.
5-aminosalicylic acid (Mesalamine) is a specific PPARγ agonist that also inhibits P21-activated kinase 1 (PAK1) and NF-κB.
PHYTO medicine. 2024 Apr 03.
Alcohol inducing macrophage M2b polarization in colitis by modulating the TRPV1-MAPK/NF-κB pathways
5-Aminosalicylic acid purchased from AbMole
Immun Inflamm Dis. 2024 Jun 20;121(18).
Banxia Xiexin decoction combined with 5-ASA protects against CPT-11-induced intestinal dysfunction in rats via inhibiting TLR4/NF-κB signaling pathway
5-Aminosalicylic acid purchased from AbMole
| Molecular Weight | 153.14 |
| Formula | C7H7NO3 |
| CAS Number | 89-57-6 |
| Solubility (25°C) | DMSO 31 mg/mL |
| Storage | 2-8°C, protect from light, sealed |
| Related NF-κB Products |
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| QNZ
QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM. |
| Caffeic Acid Phenethyl Ester
Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities. |
| Cepharanthine
Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production. |
| JSH-23
Jsh-23 is a NF-κB inhibitor, inhibited NF-κB transcriptional activity in lipopolysaccharid-stimulated macrophages RAW 264.7 with IC50 of 7.1 μM. Jsh-23 inhibited the nuclear translocation of NF-κB P65 without affecting the degradation of IκBα. |
| Methylthiouracil
Methylthiouracil is an anti-thyroid agent. Methylthiouracil inhibits TNF-α and IL-6 production and NF-κB and ERK1/2 activation. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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