| Cat.No. | Name | Information |
|---|---|---|
| M4974 | GW4869 2HCl | GW4869 (GW69A, GW554869A) is a noncompetitive inhibitor of neutral Smase (spspingolipase) with IC50 of 1 μM. GW4869 is also an inhibitor of exosome biogenesis/release, followed by endotoxin (LPS) challenge. GW4869 could effectively inhibit the generation of exosomes in macrophages and in vivo. |
| M6074 | AA26-9 | AA26-9 is a potent and broad spectrum serine hydrolase inhibitor. AA26-9 targets included serine peptidases, lipases, amidases, esterases, and thioesterases. |
| M3969 | Polydatin | Polydatin (Piceid), the glycoside of Resveratrol, is originally isolated from the Chinese herb Polygonum cuspidatum, with biological properties, such as anti-inflammation, anti-oxidative and nephroprotective effects. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses. |
| M43812 | SYN-020 | SYN-020 is an orally active recombinant bovine intestinal alkaline phosphatase (IAP) for studies related to digestive disorders. |
| M43811 | IIAEK | IIAEK is a novel cholesterol-lowering pentapeptide derived from bovine milk β-lactoglobulin that targets intestinal alkaline phosphatase (IAP) and improves cholesterol metabolism through the specific activation of IAP and down-regulation of ABCA1. Sequence: Ile-Ile-Ala-Glu-Lys |
| M42585 | Lp-PLA2-IN-12 | Lp-PLA2-IN-12 is an Lp-PLA2 inhibitor. |
| M42584 | Lp-PLA2-IN-13 | Lp-PLA2-IN-13 is a potent Lp-PLA2 inhibitor. |
| M42583 | VU0364739 | VU0364739 is a selective PLD2 inhibitor (IC50: 22 nM). |
| M42582 | Lp-PLA2-IN-14 | Lp-PLA2-IN-14 is an Lp-PLA2 inhibitor with a pIC50 of 8.4 against rhLp-PLA2. |
| M42581 | CGP-35949 sodium | CGP-35949 sodium is a LTD4 antagonist with phospholipase inhibitory activity. |
| M42580 | Palmostatin B | Palmostatin B is an Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitor. |
| M42579 | LFHP-1c | LFHP-1c is an PGAM5 inhibitor with neuroprotective activity in brain ischemic stroke. |
| M42578 | VU533 | APE-PLD (VU533) activator is a potent NAPE-PLD activator with an EC50 value of 0.30 µM. |
| M42577 | hnps-PLA-IN-1 | hnps-PLA-IN-1, a indole-3-acetamide, is a hnps-PLA2 inhibitor (IC50=0.124 μM). |
| M42576 | Efipladib | Efipladib is a potent, selective and orally active cPLA2α inhibitor with an IC50 of 0.04 μM and a Kd of 0.067 μM. |
| M42575 | nSMase2-IN-1 | nSMase2-IN-1 is an orally active Neutral sphingomyelinase 2 (nSMase2) inhibitor with an IC50 value of 0.13 ± 0.06 μM. |
| M42574 | SB-435495 | SB-435495 is a potent, selective, reversible, non-covalent and orally active Lp-PLA2 inhibitor with an IC50 of 0.06 nM. |
| M42573 | SB-435495 ditartrate | SB-435495 ditartrate is a potent, selective, reversible, non-covalent and orally active Lp-PLA2 inhibitor with an IC50 of 0.06 nM. |
| M42572 | SB-435495 hydrochloride | SB-435495 hydrochloride is a potent, selective, reversible, non-covalent and orally active Lp-PLA2 inhibitor with an IC50 of 0.06 nM. |
| M42571 | Lp-PLA2-IN-16 | Lp-PLA2-IN-16 is a lipoprotein-associated phospholipase A2 (Lp-PLA 2) inhibitor, which can be used in the research of Alzheimer's disease, etc. |
| M42570 | Lp-PLA2-IN-15 | Lp-PLA2-IN-15 is a lipoprotein-associated phospholipase A2 (Lp-PLA 2) inhibitor, which can be used in the research of Alzheimer's disease, etc. |
| M39174 | Rhamnetin | Rhamnetin is a quercetin derivative found in Coriandrum sativum, inhibits secretory phospholipase A2, with antioxidant and anti-inflammatory activity. |
| M39173 | Ikshusterol 3-O-glucoside | Ikshusterol 3-O-glucoside is a phytochemical that inhibits PLA2 from snake venoms. |
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