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Zinc Pyrithione is an anti-fungal and anti-bacterial drug that disrupts membrane transport by blocking proton pumps and is a potent copper ion carrier that can be used in copper death (cuproptosis) studies.
| Molecular Weight | 317.7 |
| Formula | C10H8N2O2S2Zn |
| CAS Number | 13463-41-7 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Sean E Mangion, et al. Targeted Delivery of Zinc Pyrithione to Skin Epithelia
[2] Cheryl Leong, et al. Effect of zinc pyrithione shampoo treatment on skin commensal Malassezia
[3] James R Schwartz. Zinc Pyrithione: A Topical Antimicrobial With Complex Pharmaceutics
[4] Mrinal Gupta, et al. Zinc therapy in dermatology: a review
| Related Cuproptosis Products |
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NSC 319726 is a p53(R175) mutant activator that inhibits the growth of p53(R175) mutant cells and acts on p53(R175) mutant cells with IC50 of 8 nM, which has no inhibition on p53 wild-type cells. NSC 319726 is a potent copper ion-carrier that can be used in cuproptosis studies. |
| Penicillamine
Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine reduces free copper and reduces oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. |
| Trientine-2HCl
Trientine-2HCl is a chelating agent used in the study of Wilson's disease by binding and scavenging copper from the body.Trientine-2HCl is also used as a chelating agent for copper in hepatocyte degeneration, as a stabilizer for epoxy resins, and as an ampholyte for isoelectric focusing. |
| 2,2'-Bipyridine
2,2'-Bipyridine has been used in the preparation of copper(II)-bipyridine-naringenin complexes. It can be used for the preparation of 2,2'-bipyridine hydrobromide. 2,2'-Bipyridine has good redox stability and glucose elevating activity. |
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