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Zatebradine(UL-FS49) is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner; 92% inhibition of the hHCN1-mediated current at 10 uM.
| Molecular Weight | 456.57 |
| Formula | C26H36N2O5 |
| CAS Number | 85175-67-3 |
| Form | Oil |
| Solubility (25°C) | 10 mM in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related HCN Channel Products |
|---|
| Ivabradine
Ivabradine is a novel medicine indicated for the symptomatic management of stable angina pectoralis. |
| Zatebradine hydrochloride
Zatebradine(UL-FS49) is a highly effective HCN ion channel antagonist, which can reversively reduce heart rate and inhibit hHCN1 up to 92% at 10uM concentration. |
| ZD7288
ZD7288 (ICI D7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker. |
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