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Cimelagatran is an orally active, selective and potent direct thrombin inhibitor. Cimelagatran is a precursor compound of the thrombin inhibitor Melagatran.
| Molecular Weight | 473.57 |
| Formula | C24H35N5O5 |
| CAS Number | 192939-46-1 |
| Form | Solid |
| Solubility (25°C) | DMSO: 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Shir-Jing Ho, et al. Ximelagatran: direct thrombin inhibitor
[2] Anirban Choudhury, et al. Ximelagatran
[3] Lisa Kwok, et al. Ximelagatran: a new type of oral anticoagulant
| Related Thrombopoietin/Thrombin Products |
|---|
| BIBR 953
BIBR 953 (Dabigatran, Pradaxa) is an oral anticoagulant from the class of the direct thrombin inhibitors. |
| Enoxaparine
Enoxaparine is a low molecular heparin that binds to antithrombin (AT) and accelerates its inhibition of factor Xa.Enoxaparine has a higher affinity for factor Xa than for thrombin, and its action on thrombin does not require HCII (heparin cofactor II). |
| Eltrombopag
Eltrombopag is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR). |
| Dabigatran Etexilate
Dabigatran Etexilate is the procompound of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule. |
| Argatroban Monohydrate
Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. |
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