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Vamorolone

Cat. No. M21092

All AbMole products are for research use only, cannot be used for human consumption.

Vamorolone Structure
Synonym:

VBP15

Size Price Availability Quantity
5mg USD 55  USD55 In stock
10mg USD 100  USD100 In stock
25mg USD 180  USD180 In stock
50mg USD 280  USD280 In stock
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Quality Control & Documentation
Biological Activity

Vamorolone (VBP15) is the first orally active dissociative steroidal anti-inflammatory and membrane stabilizer. vamorolone improves myotonic dystrophy without side effects. vamorolone inhibits (NF-κB) inhibition and reduces the effects of hormones.

Chemical Information
Molecular Weight 356.46
Formula C22H28O4
CAS Number 13209-41-1
Form Solid
Solubility (25°C) DMSO : 62.5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jean K Mah, et al. JAMA Netw Open. Efficacy and Safety of Vamorolone in Duchenne Muscular Dystrophy: A 30-Month Nonrandomized Controlled Open-Label Extension Trial

[2] Edward C Smith, et al. PLoS Med. Efficacy and safety of vamorolone in Duchenne muscular dystrophy: An 18-month interim analysis of a non-randomized open-label extension study

[3] Eric P Hoffman, et al. Neurology. Vamorolone trial in Duchenne muscular dystrophy shows dose-related improvement of muscle function

[4] Christopher R Heier, et al. Life Sci Alliance. Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy

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Keywords: Vamorolone, VBP15 supplier, GCR, inhibitors, activators

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