All AbMole products are for research use only, cannot be used for human consumption.
Valbenazine (NBI-98854) is a vesicular monoamine transporter-2 (VMAT2) inhibitor with a Ki of 110-190 nM.
| Molecular Weight | 418.57 |
| Formula | C24H38N2O4 |
| CAS Number | 1025504-45-3 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Thomas Mller. Expert Rev Neurother. Valbenazine for the treatment of tardive dyskinesia
[5] Oliver Freudenreich, et al. Clin Schizophr Relat Psychoses. Valbenazine for Tardive Dyskinesia
| Related Monoamine Transporter Products |
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| Tetrabenazine
Tetrabenazine (Ro 1-9569) is a compound for the symptomatic treatment of hyperkinetic movement disorder. |
| 13-Hydroxyisobakuchiol
Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol) is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM). |
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