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Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.
| Molecular Weight | 228.24 |
| Formula | C14H12O3 |
| CAS Number | 3902-71-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 2 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related DNA Alkylator/Crosslinker Products |
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| Apaziquone
Apaziquone is a bioreductive procompound and a chemical analog of the older chemotherapeutic agent mitomycin C. |
| Bendamustine hydrochloride
Bendamustine hydrochloride is a DNA-alkylator with a distinct pattern of activity. |
| Dacarbazine
Dacarbazine (DTIC-Dome; DTIC) is an alkylating agent that acts as a purine nucleotide precursor analog to inhibit purine nucleotide synthesis, thereby inhibiting DNA/RNA Synthesis, and can be used in studies related to melanoma and Hodgkin's lymphoma. |
| Altretamine
Altretamine is an antitumor agent which also acts as a chemosterilant for male houseflies and other insects. |
| Carmustine
Carmustine is an alkylating antineoplastic agent for inhibiting the growth of U87MG glioblastoma cells with IC50 of 1.42 μM. |
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