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TAT-P110, a peptide inhibitor of Drp1-Fis1 interaction, reduces pathology in numerous models of neurodegeneration, ischemia, and sepsis without blocking the physiological functions of Drp1.
Sequence: Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Asp-Leu-Leu-Pro-Arg-Gly-Ser
| Molecular Weight | 2412.76 |
| Formula | C100H178N44O26 |
| CAS Number | 2247617-97-4 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage | -20°C, dry, sealed |
| Related Dynamin Products |
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| Dynasore
Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM. |
| Mdivi-1
Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. |
| Hydroxy-Dynasore
Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin a heavy chain binding domain (BoNT/A-Hc). |
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