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SCH 58261 is a potent and selective A2A adenosine receptor competitive antagonist (Ki = 1.3 nM). SCH 58261 displays 323-, 53- and 100-fold selectivity over A1, A2B and A3 receptors, respectively.
Front Pharmacol. 2022 Jun 23;13:897436.
Xiaoyaosan Ameliorates Chronic Restraint Stress-Induced Depression-Like Phenotype by Suppressing A2AR Signaling in the Rat Striatum
SCH 58261 purchased from AbMole
| Molecular Weight | 345.36 |
| Formula | C18H15N7O |
| CAS Number | 160098-96-4 |
| Solubility (25°C) | DMSO 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Adenosine Receptor Products |
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Tozadenant (SYN115) is a novel, selective adenosine A(2A) receptor antagonist. |
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CGS 21680 hydrochloride is an A2A adenosine receptor agonist with an Ki of 27 nM. |
| Istradefylline
Istradefylline (KW-6002) is a potent, selective and orally active adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. |
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CGS 21680 is a selective adenosine receptor agonist for A2A and A3 with Ki of 15 ng/mL and 37 ng/mL, respectively. |
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Norisoboldine is an isoquinoline alkaloid which acts as an AhR agonist. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
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