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CGS 21680 hydrochloride is an A2A adenosine receptor agonist with Ki of 27 nM. It has affinity for A1 and A3 adenosine receptors but can be used to distinguish A2A- and A2B-mediated effects.
Front Pharmacol. 2022 Jun 23;13:897436.
Xiaoyaosan Ameliorates Chronic Restraint Stress-Induced Depression-Like Phenotype by Suppressing A2AR Signaling in the Rat Striatum
CGS 21680 hydrochloride purchased from AbMole
| Molecular Weight | 535.98 |
| Formula | C23H29N7O6.HCl |
| CAS Number | 124431-80-7 |
| Solubility (25°C) | DMSO 77 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Fernanda C Vuaden, et al. Endotoxin-induced effects on nucleotide catabolism in mouse kidney
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