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Safinamide is an orally active, selective, reversiblemonoamine oxidase-B inhibitor with both dopaminergic and non-dopaminergic (glutamatergic) properties. The IC50 value of safinamide for MAO-B is 98 nM.
| Molecular Weight | 302.34 |
| Formula | C17H19FN2O2 |
| CAS Number | 133865-89-1 |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Thomas Mller. Neurodegener Dis Manag. Safinamide in the treatment of Parkinson's disease
[2] No authors listed. Safinamide
[3] No authors listed. Aust Prescr. Safinamide for Parkinson's disease
| Related Monoamine Oxidase Products |
|---|
| Safinamide Mesylate
Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor. |
| Clorgyline hydrochloride
Clorgiline is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A). |
| Guanethidine Hemisulfate
Guanethidine Hemisulfate is an antihypertensive compound that reduces the release of catecholamines such as norepinephrine. |
| Moclobemide
Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM. |
| Nialamide
Nialamide is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class used as an antidepressant and anxiolytic. |
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