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RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function.
| Molecular Weight | 312.37 |
| Formula | C17H20N4O2 |
| CAS Number | 140405-36-3 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (Need ultrasonic) |
| Storage | Powder -20°C |
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