All AbMole products are for research use only, cannot be used for human consumption.
Progranulin is also called Proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Granulin family members are important in normal development, wound healing, and tumorigenesis. Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.
The recombinant human Progranulin comprises 587 amino acids with a predicted molecular mass of 63.2 kDa. A DNA sequence encoding the human Progranulin (NP_002078.1) (Met 1-Leu 593) with a C-terminal polyhistidine tag was expressed.
Accession: NP_002078.1
Apparent Molecular Weight: ~93.3 kDa, reducing conditions
Endotoxin < 1 EU/µg
Lyophilized from sterile PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| Related Cytokines and Growth Factors Products |
|---|
| Recombinant Human CD48/SLAMF2 (HEK293,C-Fc-6His)
Recombinant human CD48/SLAMF2 protein plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma. |
| Recombinant Human IFNγ (CHO)
Human Interferon gamma (hIFN-γ) (CHO) is a dimerized soluble cytokine that is the only member of the type II class of interferons. |
| Recombinant Human EPO Protein (CHO)
Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells. |
| Recombinant Human GM-CSF (HEK293, C-His)
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor is a hematopoietic growth factor and immune modulator. |
| Recombinant Human IL-1α Protein (E. coli)
Interleukin 1 (IL-1) is a peptide with a molecular mass of 17 kd and two isoforms, IL-1α and IL-1β. IL-1ɑ consists of 159 amino acids. Measured by its ability to induce interferon γ secretion from human natural killer lymphoma NK-92 cells, the ED50 of this effect is ≤100 ng/mL. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
