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The CD48 antigen, also known as b lymphocyte activation marker BLAST-1, the BCM1 surface antigen, Leukocyte antigens ME-102, CT.1, CD48, BCM1 and BLAST1, CD48 contain an IG-like C2-type domain and an IG-like V-type domain, but no transmembrane domain. Instead, a GPI anchor site is spliced through a C-terminal domain to form soluble receptors on the cell surface. CD48 may promote the interaction between activated lymphocytes and participate in the regulation of T cell activation. CD48 plays an important role in regulating the number of progenitor cells and inhibiting tumor development as an environmental sensor. These results suggest that anti-CD48 mab may be an effective mab in the treatment of multiple myeloma.
Recombinant Human SLAM Family Member 2 expressed the target gene encoding Gln27-Ser220 with a human IgG1 Fc, 6His tag at the C-terminus.
Accession: P09326
Apparent Molecular Weight: 71 KDa, reducing conditions
Endotoxin < 1 EU/µg
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
| Formula | |
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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