Free shipping on all orders over $ 500

PXS-5153A 

Cat. No. M29270

All AbMole products are for research use only, cannot be used for human consumption.

PXS-5153A  Structure
Size Price Availability Quantity
5mg USD 330  USD330 In stock
10mg USD 500  USD500 In stock
25mg USD 850  USD850 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

PXS-5153A is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A could reduce crosslinks and ameliorates fibrosis.

Chemical Information
Molecular Weight 475.41
Formula C20H25Cl2FN4O2S
CAS Number 2125956-82-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Yordanos F I Setargew, et al. Cancers (Basel). Targeting Lysyl Oxidase Family Meditated Matrix Cross-Linking as an Anti-Stromal Therapy in Solid Tumours

[2] Heidi Schilter, et al. J Cell Mol Med. The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis

Related Monoamine Oxidase Products
Safinamide Mesylate

Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor.

Clorgyline hydrochloride

Clorgiline is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A).

Guanethidine Hemisulfate

Guanethidine Hemisulfate is an antihypertensive compound that reduces the release of catecholamines such as norepinephrine.

Moclobemide

Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM.

Nialamide

Nialamide is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class used as an antidepressant and anxiolytic.

  Catalog
Abmole Inhibitor Catalog




Keywords: PXS-5153A  supplier, Monoamine Oxidase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.