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Phox-I2

Cat. No. M42523

All AbMole products are for research use only, cannot be used for human consumption.

Phox-I2 Structure

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Quality Control & Documentation
Biological Activity

Phox-I2 is a selective inhibitor of p67phox-Rac1 interaction, binds to p67phox with high affinity with a Kd of ~150 nM.

Chemical Information
Molecular Weight 337.33
Formula C18H15N3O4
CAS Number 353495-22-4
Form Solid
Solubility (25°C) DMSO 200 mg/mL (Need ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xuan Wang et al. PLoS One. The novel NADPH oxidase 4 selective inhibitor GLX7013114 counteracts human islet cell death in vitro

[2] Wei-Ran Gen et al. Life Sci. Linagliptin improved myocardial function recovery in rat hearts after a prolonged hypothermic preservation

[3] Judith Hagenbuchner et al. Sci Rep. Very long-/ and long Chain-3-Hydroxy Acyl CoA Dehydrogenase Deficiency correlates with deregulation of the mitochondrial fusion/fission machinery

[4] Sharifah Syed Mortadza et al. Sci Rep. Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells

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  Catalog
Abmole Inhibitor Catalog




Keywords: Phox-I2 supplier, NADPH Oxidase, inhibitors, activators

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