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Palifosfamide

Cat. No. M11549

All AbMole products are for research use only, cannot be used for human consumption.

Palifosfamide Structure
Synonym:

Isophosphoramide mustard; IPM; ZIO-201

Size Price Availability Quantity
5mg USD 200  USD200 In stock
10mg USD 340  USD340 In stock
50mg USD 585  USD585 In stock
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Quality Control & Documentation
Biological Activity

Palifosfamide(Isophosphoramide mustard; IPM; Zio-201) is a new DNA alkylation agent and active metabolite of isocyclophosphamide, which has anticancer activity.

Chemical Information
Molecular Weight 221.02
Formula C4H11Cl2N2O2P
CAS Number 31645-39-3
Form Solid
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage -20°C, protect from light, dry, sealed
References

[1] Barry Jones, et al. Anticancer Drugs. Anticancer activity of stabilized palifosfamide in vivo: schedule effects, oral bioavailability, and enhanced activity with docetaxel and doxorubicin

[2] Susanne Jung, et al. IDrugs. Palifosfamide, a bifunctional alkylator for the treatment of sarcomas

[3] Pooja Hingorani, et al. Cancer Chemother Pharmacol. Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma

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Keywords: Palifosfamide, Isophosphoramide mustard; IPM; ZIO-201 supplier, DNA Alkylator/Crosslinker, inhibitors, activators

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