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Olivetol

Cat. No. M17348

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Olivetol Structure
Size Price Availability Quantity
50mg USD 40  USD40 In stock
100mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2. Olivetol also inhibits CYP2C19 and CYP2D6 activity, with IC50s of 15.3 μM, 7.21 μM and Kis of 2.71 μM, 2.87 μM, respectively.

Chemical Information
Molecular Weight 180.24
Formula C11H16O2
CAS Number 500-66-3
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Antonella Brizzi, et al. Bioorg Med Chem. Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity

[2] Lewis J Kearsey, et al. FEBS J. Structure of the Cannabis sativa olivetol-producing enzyme reveals cyclization plasticity in type III polyketide synthases

[3] Xiaozhou Luo, et al. Nature. Complete biosynthesis of cannabinoids and their unnatural analogues in yeast

[4] Giovanni Appendino, et al. J Nat Prod. Antibacterial cannabinoids from Cannabis sativa: a structure-activity study

[5] R H McClanahan, et al. J Nat Prod. Biotransformation of olivetol by Syncephalastrum racemosum

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Keywords: Olivetol supplier, Cannabinoid, inhibitors, activators

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