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Mazdutide (IBI362, LY3305677) is a novel glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist. Mazdutide (IBI362, LY3305677) was well tolerated. It can be used in studies of obesity and type 2 diabetes (T2D).
| CAS Number | 2259884-03-0 (free base) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Glucagon Receptor Products |
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PF-06291874 is an orally active, potent and selective glucagon receptor antagonist. |
| GRA Ex-25
GRA Ex-25 is an inhibitor of glucagon receptor, with IC50 values of 56 and 55 nM for rat and human glucagon receptors, respectively. |
| Glucagon (1-29), bovine, human, porcine
Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation. |
| NNC0640
NNC0640 is a potent, negative allosteric modulator (NAM) of human G-protein-coupled glucagon receptor (GCGR) with IC50 of 69.2 nM. |
| Dasiglucagon acetate
Dasiglucagon acetate is a Glucagon Receptor Agonist. The physiologic effect of dasiglucagon is by means of Increased Glycogenolysis. |
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