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Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation. Glucagon is a peptide hormone that helps regulate the blood sugar (glucose) levels in the body. Glucagon binds to the glucagon receptors, the liver cells convert the glycogen into individual glucose molecules and release them into the bloodstream, in a process known as glycogenolysis.
Patent. JP2024525144A 2024 Jul 10.
Patent. JP2024525144A
Glucagon (1-29), bovine, human, porcine purchased from AbMole
Patent. WO2022262837A1 2022 Dec 22.
Patent. WO2022262837A1
Glucagon (1-29), bovine, human, porcine purchased from AbMole
| Molecular Weight | 3482.75 |
| Formula | C153H225N43O49S |
| CAS Number | 16941-32-5 |
| Solubility (25°C) | DMSO 1 mg/mL Water 5 mg/mL (ultrasonic and adjust pH to 3 with HCl) |
| Storage | -20°C, protect from light, dry, sealed |
| Related Glucagon Receptor Products |
|---|
| PF-06291874
PF-06291874 is an orally active, potent and selective glucagon receptor antagonist. |
| GRA Ex-25
GRA Ex-25 is an inhibitor of glucagon receptor, with IC50 values of 56 and 55 nM for rat and human glucagon receptors, respectively. |
| NNC0640
NNC0640 is a potent, negative allosteric modulator (NAM) of human G-protein-coupled glucagon receptor (GCGR) with IC50 of 69.2 nM. |
| Dasiglucagon acetate
Dasiglucagon acetate is a Glucagon Receptor Agonist. The physiologic effect of dasiglucagon is by means of Increased Glycogenolysis. |
| Adomeglivant
Adomeglivant (LY2409021) is a potent, selective glucagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus. |
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