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Linoleoyl ethanolamide

Cat. No. M30475

All AbMole products are for research use only, cannot be used for human consumption.

Linoleoyl ethanolamide Structure
Synonym:

Linoleic acid monoethanolamide

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Quality Control & Documentation
Biological Activity

Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1（CB1）and CB2 receptors, and inhibits the binding of [3H]CP-55,940 with Kis of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time.

Chemical Information
Molecular Weight 323.51
Formula C20H37NO2
CAS Number 68171-52-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Isabelle Dubuc, et al. Front Immunol. Cytokines and Lipid Mediators of Inflammation in Lungs of SARS-CoV-2 Infected Mice

[2] Ailing Liu, et al. Microbiol Spectr. Adjunctive Probiotics Alleviates Asthmatic Symptoms via Modulating the Gut Microbiome and Serum Metabolome

[3] Xin-Yun Tian, et al. Front Cell Infect Microbiol. 919 Syrup Alleviates Postpartum Depression by Modulating the Structure and Metabolism of Gut Microbes and Affecting the Function of the Hippocampal GABA/Glutamate System

[4] Xiaosan Wang, et al. J Oleo Sci. Synthesis of linoleoyl ethanolamide

[5] Tsukasa Ishida, et al. Eur J Pharmacol. Linoleoyl ethanolamide reduces lipopolysaccharide-induced inflammation in macrophages and ameliorates 2,4-dinitrofluorobenzene-induced contact dermatitis in mice

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Keywords: Linoleoyl ethanolamide, Linoleic acid monoethanolamide supplier, Cannabinoid, inhibitors, activators

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