All AbMole products are for research use only, cannot be used for human consumption.
LCZ696, consisting of Valsartan and Sacubitril in a 1:1 molar ratio, is a first-in-class dual-action angiotensin receptor-neprilysin inhibitor (ARNi,angiotensin receptor-neprilysin inhibitor) for the study of hypertension and heart failure.
BMC Cardiovasc Disord. 2024 Feb 14;24(1):106.
Sacubitril/valsartan inhibits the proliferation of vascular smooth muscle cells through notch signaling and ERK1/2 pathway
LCZ696 purchased from AbMole
| Molecular Weight | 915.98 |
| Formula | C24H29N5O3.C24H29NO5.5/2H2O.3Na |
| CAS Number | 936623-90-4 |
| Solubility (25°C) | Water 50 mg/mL DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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