All AbMole products are for research use only, cannot be used for human consumption.
Kartogenin induces chondrocyte differentiation from hMSCs by enhancing the nuclear localization of CBFβ, and protects articular chondrocytes.Kartogenin promotes cartilage repair in collagenase VII (10 μM)– and surgery (100 μM)-induced OA models in mice.
Int J Nanomedicine. 2022 Nov 21;17:5511-5524.
Magnetically Guided Intracartilaginous Delivery of Kartogenin Improves Stem Cell-Targeted Degenerative Arthritis Therapy
Kartogenin purchased from AbMole
| Molecular Weight | 317.34 |
| Formula | C20H15NO3 |
| CAS Number | 4727-31-5 |
| Solubility (25°C) | DMSO 53 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Johnson K, et.al Science. A stem cell-based approach to cartilage repair.
| Related TGF-beta/Smad Products |
|---|
| Pirfenidone
Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone inhibits TGF-β bioactivity by affecting TGF-β2 mRNA expression and processing of pro-TGF-β in CCL-64 cells. Pirfenidone (AMR69) attenuates CCL2 and CCL12 production in fibrocyte cells. |
| Asiaticoside
Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. |
| Amygdalin
Laetrile is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds. |
| Norcantharidin
Norcantharidin |
| SIS3 hydrochloride
SIS3 hydrochloride is a novel specific inhibitor of TGF-β1/ALK-5 phosphorylation of Smad3 with an IC50 of 3 µM. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
