All AbMole products are for research use only, cannot be used for human consumption.
Firibastat (QGC001) is an orally active EC33 precursor drug. Firibastat is A first-in-class (first-in-class) brain aminopeptidase A (APA) inhibitor (Ki=200 nM) that selectively and specifically inhibits the conversion of cerebral angiotensin II to angiotensin III and lowers blood pressure in hypertensive rats.
| Molecular Weight | 368.51 |
| Formula | C8H20N2O6S4 |
| CAS Number | 648927-86-0 |
| Solubility (25°C) | Wate ≥ 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Shawna D Nesbitt. Curr Hypertens Rep. Firibastat: a Novel Treatment for Hypertension
| Related Aminopeptidase Products |
|---|
| Ubenimex
Ubenimex, also known as bestatin, is a competitive protease inhibitor. |
| Tosedostat
CHR-2797 is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively. |
| Acebilustat
Acebilustat is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory drug. |
| TNP-470
TNP-470 (AGM-1470; NSC 642492) is a synthetic analog of fumagillin (or Fumagillol) and a methionine aminopeptidase-2 inhibitor. |
| L-Leucinol
L-Leucinol ((+)-Leucinol) is a potent, competitive leucine aminopeptidase inhibitor with Ki value of 17 μM. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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