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EN219 is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination.
| Molecular Weight | 456.56 |
| Formula | C17H13Br2ClN2O |
| CAS Number | 380351-29-1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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| CC0651
CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme and inhibited the ubiquitination of p27Kip1 with IC50 value of 1.72 μM. |
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| Ginkgolic Acid
Ginkgolic Acid is a inhibits SUMOylation by binding E1. |
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