All AbMole products are for research use only, cannot be used for human consumption.
EB-3D is a potent and selective choline kinase α (ChoKα) inhibitor, with an IC50 of 1 μM for ChoKα1. EB-3D exerts effects on ChoKα expression, AMPK activation, apoptosis, endoplasmic reticulum stress and lipid metabolism. EB-3D exhibits a potent antiproliferative activity in a panel of T-leukemia cell lines. Anti-cancer activity.
| Molecular Weight | 644.44 |
| CAS Number | 1839150-63-8 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage | 2-8°C, dry, sealed |
| Related AMPK Products |
|---|
| Dorsomorphin dihydrochloride
Dorsomorphin (BML-275; Compound C) dihydrochloride is a potent inhibitor of AMP-activated protein kinase (AMPK), with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride induces autophagy. |
| OTSSP167
OTSSP167 is a highly potent MELK (maternal embryonic leucine zipper kinase) inhibitor with IC50 of 0.41 nM. |
| WZ4003
WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively, without significant inhibition on 139 other kinases. |
| Geniposide
Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis. |
| Metformin
Metformin (1, 1-dimethylbiguanide) inhibits mitochondrial respiratory chains in the liver, leads to AMPK activation and enhances insulin sensitivity, and can be used in type 2 diabetes research. Metformin can cross the blood-brain barrier and induce autophagy, and Metformin is a CD47 inhibitor in vitro. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
