All AbMole products are for research use only, cannot be used for human consumption.
Chlorpromazine hydrochloride is an antagonist of D2, 5HT2A, potassium and sodium channels. The Ki of Chlorpromazine Hydrochloride to D2 and 5HT2A were 363 nM and 8.3 nM, respectively. Chlorpromazine hydrochloride also blocks hNav1.7 channels (IC50=25.9 μM; concentration-dependent) and HERG potassium channels (IC50=21.6 μM). Chlorpromazine also excites the 20S proteasome. Chlorpromazine hydrochloride also can inhibit clathrin-mediated endocytosis.
*The compound is unstable in solutions, freshly prepared is recommended.
J Control Release. 2025 May 30; .
Microneedle-mediated biomimetic nanoparticles for targeted antioxidant and anti-inflammatory therapy in age-related macular degeneration
Chlorpromazine hydrochloride purchased from AbMole
Med Microbiol Immunol. 2024 Oct 23;213(1):23.
The pathogenic responses elicited during exposure of human intestinal cell line with Giardia duodenalis excretory-secretory products and the potential attributed endocytosis mechanism
Chlorpromazine hydrochloride purchased from AbMole
Mater Adv. 2024 Jul 18.
MiRNA-20a-loaded graphene oxide–polyethylenimine enters bone marrow mesenchymal stem cells via clathrin-dependent endocytosis for efficient osteogenic differentiation
Chlorpromazine hydrochloride purchased from AbMole
Small. 2023 Mar 12;e2208063.
2D MoS2 Nanosheets Induce Ferroptosis by Promoting NCOA4-Dependent Ferritinophagy and Inhibiting Ferroportin
Chlorpromazine hydrochloride purchased from AbMole
J Med Virol. 2023 Jan;95(1).
Enterovirus-71 utilizes small extracellular vesicles to cross the blood-brain barrier for infecting the central nervous system via transcytosis
Chlorpromazine hydrochloride purchased from AbMole
| Molecular Weight | 355.33 |
| Formula | C17H19ClN2S.HCl |
| CAS Number | 69-09-0 |
| Form | Solid |
| Solubility (25°C) | Water 90 mg/mL DMSO ≥ 60 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
| Related Potassium Channel Products |
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| TAK-438
TAK-438 is a novel and potent potassium-competitive acid blocker (P-CAB) with IC50 of 19 nM. |
| ML133 hydrochloride
ML133 hydrochloride is a selective inhibitor of the Kir2 family of inward rectifier (IRK, KCNJ) potassium channels. |
| Doxapram hydrochloride hydrate
Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively. |
| Gliquidone
Gliquidone is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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