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Cbl-b-IN-1 is an inhibitor of Cbl-b, with an IC50 of less than 100 nM. Cbl-b-IN-1 can promote the secretion of cytokines such as IL-2, IFN-γ, and TNF-α, facilitate T cell activation, and enhance the TCR signaling pathway.
| Molecular Weight | 498.62 |
| Formula | C29H34N6O2 |
| CAS Number | 2368841-84-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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| Ginkgolic Acid
Ginkgolic Acid is a inhibits SUMOylation by binding E1. |
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