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Brusatol (Brutasol) is a plant-derived natural quassinoid that exhibits broad cytotoxicity in cancer cultures (IC50 <1 μM against 457 cancer cell lines) by inhibiting de novo synthesis of cellular proteins (Effective conc. <50 nM in A549 cells), including NRF2.
Cytokine. 2023 Oct 3;172:156375.
Thymoquinone attenuates inflammation in C. Albicans keratitis by activating Nrf2/HO-1 signaling pathway and reducing fungal load
Brusatol purchased from AbMole
| Molecular Weight | 520.53 |
| Formula | C26H32O11 |
| CAS Number | 14907-98-3 |
| Solubility (25°C) | DMSO 25 mg/mL (ultrasonic) |
| Storage | 2-8°C, protect from light, sealed |
[4] Sabrina J Cai, et al. Brusatol, an NRF2 inhibitor for future cancer therapeutic
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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