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Bendamustine (SDX-105 free base), a purine analogue, is a DNA cross-linking agent. Bendamustine activates DNA-damage stress response and apoptosis. Bendamustine has potent alkylating, anticancer and antimetabolite properties.
| Molecular Weight | 358.26 |
| CAS Number | 16506-27-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | -20°C, protect from light |
| Related DNA Alkylator/Crosslinker Products |
|---|
| Apaziquone
Apaziquone is a bioreductive procompound and a chemical analog of the older chemotherapeutic agent mitomycin C. |
| Bendamustine hydrochloride
Bendamustine hydrochloride is a DNA-alkylator with a distinct pattern of activity. |
| Dacarbazine
Dacarbazine (DTIC-Dome; DTIC) is an alkylating agent that acts as a purine nucleotide precursor analog to inhibit purine nucleotide synthesis, thereby inhibiting DNA/RNA Synthesis, and can be used in studies related to melanoma and Hodgkin's lymphoma. |
| Altretamine
Altretamine is an antitumor agent which also acts as a chemosterilant for male houseflies and other insects. |
| Carmustine
Carmustine is an alkylating antineoplastic agent for inhibiting the growth of U87MG glioblastoma cells with IC50 of 1.42 μM. |
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