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AZD9567

Cat. No. M13973

All AbMole products are for research use only, cannot be used for human consumption.

AZD9567 Structure
Synonym:

Mizacorat

Size Price Availability Quantity
1mg USD 250  USD250 In stock
5mg USD 600  USD600 In stock
10mg USD 850  USD850 In stock
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Biological Activity

AZD9567 (Mizacorat) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation.

Chemical Information
Molecular Weight 494.53
CAS Number 1893415-00-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xueping Hu, et al. Discovery of Novel GR Ligands toward Druggable GR Antagonist Conformations Identified by MD Simulations and Markov State Model Analysis

[2] Haiyi Chen, et al. Molecular View on the Dissociation Pathways and Transactivation Regulation Mechanism of Nonsteroidal GR Ligands

[3] Joachim Almquist, et al. Estimation of Equipotent Doses for Anti-Inflammatory Effects of Prednisolone and AZD9567, an Oral Selective Nonsteroidal Glucocorticoid Receptor Modulator

[4] Lena Ripa, et al. Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile

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Keywords: AZD9567, Mizacorat supplier, GCR, inhibitors, activators

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