All AbMole products are for research use only, cannot be used for human consumption.
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.
| Molecular Weight | 766.27 |
| Formula | C48H95NO5 |
| CAS Number | 2036272-55-4 |
| Solubility (25°C) | DMSO 50 mg/mL Ethanol 80 mg/mL |
| Storage | 4°C, protect from light |
[2] S Moein Moghimi. Mol Ther. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines
| Related Liposome Products |
|---|
| Sunflower phospholipids
Sunflower phospholipids can be used for the preparation of liposomes. It has been shown to play important roles in many important areas, including maintenance of cellular structure, fat metabolism, memory, nerve signaling, acting as a precursor of important neurotransmitters, and liver health. |
| β-Sitosterol
Replacing cholesterol in lipid nanoparticle (LNP) formulations with β-Sitosterol, a natural phytosterol, significantly improves mRNA delivery. |
| DLPC
DLPC is a lRH-1 agonist; regulates bile acid metabolism. |
| DLin-MC3-DMA
DLin-MC3-DMA is the most potent cationic lipid that has been synthesized for lipid nanoparticles (LNPs) to deliver the siRNA. |
| DLinDMA
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
