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2-Chloroadenosine is a selective A1 adenosine receptor agonist. 2-Chloroadenosine is an apparent competitive inhibitor of uridine influx (apparent Ki=33 μM) and high-affinity nitrobenzylthioinosine binding (apparent Ki=0.18 mM). 2-Chloroadenosine is a transported permeant for the nucleoside transporter in human erythrocytes.
| Molecular Weight | 301.69 |
| Formula | C10H12ClN5O4 |
| CAS Number | 146-77-0 |
| Solubility (25°C) | DMSO 90 mg/mL Water 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] I Bellezza, et al. 2-Chloroadenosine and human prostate cancer cells
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