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Anti-infection Anti-infection

Cat.No.  Name Information
M1959 Oseltamivir Oseltamivir is a potent and selective inhibitor of influenza virus neuraminidase enzyme.
M5055 Peramivir Peramivir is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
M1707 Entecavir Monohydrate Entecavir Hydrate is a class of antiviral compounds.
M3357 Telbivudine Telbivudine (Epavudine) is an orally active, potent antiviral inhibitor of hepatitis B virus (HBV) replication. Telbivudine is an antiviral compound used in hepatitis B research.
M1695 Cidofovir Cidofovir (Vistide) is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis.
M4718 Dendrobine Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine has antiviral activity against influenza A virus, IC50 values for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2) were 3.39 μM, 2.16 μM and 5.32 μM, respectively.
M3222 Peramivir Trihydrate Peramivir Trihydrate is a trihydrate of the anti-infection agent peramivir (RWJ-270201,BCX-1812) which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
M4789 Isoscopoletin Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active ingredient in artemisia argyi leaves. Isoscopoletin showed significant inhibition of cell proliferation, with IC50 values of 4.0 μM and 1.6 μM against human CCRF-CEM leukemia cells and CEM/ADR5000 drug-resistant subline, respectively. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) has the activity of inhibiting HBV replication.
M10082 Amodiaquine Amodiaquine is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent.
M7775 3-Deazaadenosine 3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM, possesses antiviral activity inhibitor of leukocyte adhesion to TNF-treated endothelial cells.
M43911 Tachyplesin I Tachyplesin I is a cationic antimicrobial peptide containing 17 amino acid residues.
M41176 TMC647055 TMC647055 is a potent nonnucleoside NS5B polymerase inhibitor of HCV replication.
M40860 Bucillamine Bucillamine is an orally active endogenous cysteine derivative of the amino acid that also acts as a sulfhydryl donor with antiangiogenic, antioxidant, and anti-inflammatory activities, and is used in rheumatoid arthritis (RA), cystinuria, and gout studies.
M40808 β-Amyrin acetate β-Amyrin acetate is a triterpenoid natural product that localizes to HMG CoA reductase and inhibits its activity, with potent anti-inflammatory, anti-fungal, anti-diabetic, and anti-hyperlipidemic activities.
M40759 Human β-defensin 1 Human β-defensin 1 is a member of a family of naturally occurring antimicrobial peptides produced by epithelial cells that have antimicrobial activity and can be used in studies related to autoimmune diseases.
M40724 3-Chloro-L-alanine 3-Chloro-L-alanine is an inhibitor of kynureninase as well as an inhibitory amino acid analog that inhibits the activity of several enzymes (e.g. threonine deaminase, alanine racemase).
M40629 Calcium trinatrium diethylenetriaminepentaacetic acid hydrate Calcium trinatrium diethylenetriaminepentaacetic acid hydrate is a cytomegalovirus CMV replication inhibitor, chelator, heavy metal detoxifier (e.g., acute cadmium toxicity), and radioactivity promoter, which improves solubility by forming water-soluble chelates with polyvalent cations.
M40613 Methylenedisalicylic acid Methylenedisalicylic acid is a potent inhibitor of MarR family transcription factor A (MgrA) and Ser/Thr kinase (Stp1) that enhances SarA/MgrA phosphorylation through inhibition of Staphylococcus aureus Stp1, with an IC50 value of 9.68 ± 0.52 μM when acting on Stp1.In addition, Methylenedisalicylic acid can also be used as a lead compound in the study of methods to reduce staphylococcal toxicity.
M38807 Umifenovir Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro.
M38767 Abyssinone V Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity.
M38764 Indinavir Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CLpro inhibitor.
M38760 Glycoborinine Glycoborinine, a natural carbazole alkaloid, can be isolated from Glycosmis pentaphylla. Glycoborinine induces HepG2 cell apoptosis through mitochondrial pathway. Glycoborinine also inhibits HIV replication in cells.
M38750 γ-Fagarine γ-Fagarine is a furoquinoline alkaloid naturally occurring in Rutae Herba. γ-Fagarine has strong anti-HCV activities with IC50 of 20.4 μg/mL and is also a sister chromatid exchanges (SCEs) inducer.
M31392 alpha-Terpineol alpha-Terpineol is a monoterpene alcohol with broad-spectrum antitumor activity that blocks the expression of NF-kB in tumor cell growth.
M31341 Omiganan TFA Omiganan is a novel synthetic cationic antimicrobial peptide containing 12 amino acids, as well as a synthetic analog of indolemycin, with broad-spectrum antimicrobial and antibiofilm activity. It can be used in studies related to atopic rhinitis.
M31340 Peceleganan acetate Peceleganan (antimicrobial peptide PL-5) is a chemically synthesized, alpha-helical antimicrobial peptide containing 26 amino acid residues.
M30963 TTP-8307  TTP-8307 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP).
M30553 Bifendate Bifendate (DDB) is a synthetic intermediate of Schisandrin C with anti-HBV efficacy in research of chronic hepatitis B.
M30221 Ferruginol Ferruginol ((+)-Ferruginol), a natural diterpenoid, is an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). Ferruginol inhibits the growth of thyroid cancer cells through the induction of mitochondrial apoptosis. Ferruginol has antitumor, cardioprotective, antioxidant, gastroprotective, and neuroprotective activities.
M30140 Inarigivir Inarigivir (ORI-9020) is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) act as a RIG-I agonist to activate cellular innate immune responses.




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