Free shipping on all orders over $ 500

Zoniporide hydrochloride

Cat. No. M29629

All AbMole products are for research use only, cannot be used for human consumption.

Zoniporide hydrochloride Structure
Synonym:

CP-597396 hydrochloride

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.

Quality Control & Documentation
Biological Activity

Zoniporide (CP-597396) hydrochloride is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride inhibits human NHE-1 (IC50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59 nM).

Chemical Information
Molecular Weight 356.81
Formula C17H17ClN6O
CAS Number 241800-97-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Gabriela Castañeda-Corral, et al. Brain Res. Blockade of peripheral and spinal Na+/H+ exchanger increases formalin-induced long-lasting mechanical allodynia and hyperalgesia in rats

[2] Ravi B Marala, et al. Eur J Pharmacol. Zoniporide: a potent and highly selective inhibitor of human Na(+)/H(+) exchanger-1

Related Na+/H+ Exchanger (NHE) Products
Tenapanor

Tenapanor is an inhibitor of the Na+/H+ exchanger NHE3 with IC50 values of 5 and 10 nM against human and Rat NHE3, respectively.
KR-32568

KR-32568 is a sodium/hydrogen exchanger-1 (NHE-1) inhibitor with an IC50 value of 0.23 μM.
Cariporide

Cariporide is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter.
EMD-87580

EMD-87580 is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter.
FR183998 free base

FR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively.
  Catalog
Abmole Inhibitor Catalog




Keywords: Zoniporide hydrochloride, CP-597396 hydrochloride supplier, Na+/H+ Exchanger (NHE) , inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.