All AbMole products are for research use only, cannot be used for human consumption.
Zn-c3 is an orally active, highly potent and selective Wee1 inhibitor (IC50=3.9 nM). Zn-c3 could be used in cancer research.
| Molecular Weight | 526.63 |
| Formula | C29H34N8O2 |
| CAS Number | 2376146-48-2 |
| Solubility (25°C) | DMSO ≥ 200 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Wee1 Products |
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| Adavosertib (MK-1775)
Adavosertib (AZD1775, MK-1775) is a small pyrazolacil derivative, an effective ATP competitive specific inhibitor of WEE1 kinase, with IC50 of 5.2 nM. It can inhibit G2 phase DNA damage test sites. |
| RP-6306
RP-6306 (Lunresertib) is the first-in-class, highly potent and selective PKMYT1 inhibitor that preferentially kills tumor cells overexpressing CCNE1 and was shown to inhibit the growth of a broad range of CCNE1-amplified tumors in xenograft/PDX preclinical models, both as a single agent and in combination therapy settings. |
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Products are for research use only. Not for human use. We do not sell to patients.
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