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ZLD115

Cat. No. M42400

All AbMole products are for research use only, cannot be used for human consumption.

ZLD115 Structure

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Quality Control & Documentation
Biological Activity

ZLD115 is a FB23-derivated inhibitor of Fat Mass and Obesity-associated Protein (FTO).

Chemical Information
Molecular Weight 496
Formula C27H30ClN3O4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Pan Xiao et al. J Med Chem. Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties

Related FTO Products
Entacapone

Entacapone is an inhibitor of FTO demethylation with IC50 of 3.5 μM, Entacapone also inhibits catechol-O-methyltransferase (COMT) with IC50 of 151 nM.

Rhein

Rhein, also known as cassic acid, is a substance in the anthraquinone group obtained from rhubarb.

FB23

FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. FB23 binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.

FB23-2

FB23-2 is a potent and selective FTO inhibitor with an IC50 of 2.6 μM, directly binds to FTO and selectively inhibit FTO's m6A demethylase activity.

Dac51

Dac51 is an effective FTO inhibitor with an IC50 of 0.4 μM against FTO demethylation.

  Catalog
Abmole Inhibitor Catalog




Keywords: ZLD115 supplier, FTO, inhibitors, activators

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