All AbMole products are for research use only, cannot be used for human consumption.
YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM).
| Molecular Weight | 600.11 |
| CAS Number | 1936529-65-5 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 75 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Marc N Wein, et al. SIKs control osteocyte responses to parathyroid hormone
| Related Salt-inducible Kinase Products |
|---|
| HG-9-91-01
HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIK) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively. |
| ARN-3236
Arn-3236 is a selective inhibitor of salt-induced kinase 2 (SIK2) with an IC50 value of <1 nM, 21.63 nM and 6.63 nM against SIK2, SIK1 and SIK3, respectively. It has antitumor activity. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
